SGN-LIV1A

About SGN-LIV1A

SGN-LIV1A is an auristatin-based ADC using the same drug-linker as brentuximab vedotin. It is targeted to LIV-1, a protein that is expressed in several types of solid tumors, including more than 90 percent of breast cancers. Preclinical data have demonstrated significant antitumor activity in multiple cancer models.

Status

SGN-LIV1A is being evaluated in a phase 1 clinical trial for patients with LIV-1-positive metastatic breast cancer.

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